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The four-story Hampton Inn is located in Cape Girardeau, off I-55 at Exit #96 (Route K/William Street) in Southeastern Missouri. Cape Girardeau is 100 miles south of St. Louis and 170 miles north of Memphis, TN. Our convenient location at the southeastern corner of I-55 & Route K is just 4.5 miles from downtown Cape Girardeau and 6 miles from Cape Girardeau Regional Airport. Southeast Missouri State University (4 miles), Show Me Center (4.5 miles), Isle of Capri Casino (4.5 miles), St. Francis Hospital (1 block) and Southeast Missouri Hospital (4 miles) are all easily accessible. In the hotel complex (easy walking distance) is the Plaza Conference Center, Red Lobster, Olive Garden, Popeyes Chicken, Panera Bread, Honey Baked Ham, Cracker Barrel, Texas Roadhouse and Bella Donna Salon. We are also very convenient for business travelers with access to Procter & Gamble (18 miles), Doctors Park Complex (1 block), Mondi (18 miles), Rubbermaid (9 miles) Southeast Missouri Regional Port Authority (6 miles) and Biokyowa (7 miles). Local attractions include Shawnee Park Sports Complex (3 miles), Mississippi River & Missouri Wall of Fame Mural (5 miles), Cape Splash Family Aquatic Center (3 miles), Westpark Mall (1 block), Lewis & Clark Red House Interpretive Center (5 miles), Historic Bollinger Mill (16 miles), Glenn House (4 miles), Fort D (4.5 miles), SEMO River Campus (4.5 miles), Arena Park (3 miles), Trail of Tears State Park (15 miles), Dalhousie Golf Course (4 miles), Bent Creek Golf Course (10 miles), Steele Crest Winery (9 miles) and River Ridge Winery (10 miles).
incredible service at our Cape Girardeau, MO hotel. From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William Street, our hotel complex includes various shopping and dining options. Walk to seven restaurants within the complex such as Cracker Barrel, Texas Roadhouse and Panera Bread. This beautiful new hotel offers all the amenities you need while traveling. Start your day with a quick workout in the fitness room or with some laps in the heated indoor pool. Sit down to a free, hot breakfast served daily with items including fresh baked waffles, eggs, biscuits and gravy and rotating options. If youre pressed for time, grab Hamptons On the Run Breakfast Bags, available Monday through Friday. Stay connected to the office with free WiFi in every room or work in the business center with two computer terminals and printing capabilities. End your day at our nightly cookie hour with warm cookies, cold milk and friendly team members available for your questions or concerns. Rest comfortably on a clean and fresh Hampton bed watching the 37-inch HDTV or with your laptop on the provided lap desk.