Interested in accommodations in Cape Girardeau, MO? Hotels-Rates has all the info you need to locate the perfect hotel in Cape Girardeau. Hotels-Rates boasts a comprehensive data collection related to all kinds of places all across the U. S. , from parks, malls and golf courses to convention centers, hospitals and sports venues. We will help you find the best hotel, at the best price, in the perfect location, with all the conveniences and amenities you need. Simply navigate to any of our point of interest pages where you can find detailed, frequently updated data on close-by hotel prices and locations. Cape Girardeau, MO is also home to Southeast Missouri State University, so if you’re taking a tour of the school or are a fan coming to watch a game, we can help you find a place to stay near the school.