- 29 Available Hotels Near I-81 and I-66
- Rates Starting at just $49.99
- 22 Chains To Choose From
- Last Minute Inventory!
Looking for a hotel around I-81 and I-66 in Middletown, VA? Hotels-Rates has you covered with everything you want to know about lodging and hotels around this exit and elsewhere in Middletown. Whether you are traveling on vacation or for work, Hotels-Rates has info on all the things to do, attractions and accomodations in Middletown. Driving in to tour the campus? Shenandoah University and Christendom College are nearby the exit, with Shenandoah University being the closest to the exit.