Find the Best Accommodations in Charleston, MO

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Charleston, MO, USAdd DatesChange Search
Destination: Charleston, MO, US(change)
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  • 29 Available Charleston Hotels
  • Rates Starting at just $54.99
  • 15 Chains To Choose From
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Super 8 by Wyndham Charleston MO
$68
starstar
0 Reviews
310 South Story St Charleston, MO
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Quality Inn Charleston I-57
$75
starstar
Good 3.5   67 Reviews
102 Drake St Charleston, MO
  • Pet Friendly
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Eagle Inn Charleston
$70
starstar
0 Reviews
2811 East Marshall Street Charleston, MO
  • Pet Friendly
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Comfort Inn & Suites Sikeston I-55
$97
starstar
Good 3.5   130 Reviews
109 Matthews Ln Sikeston, MO
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Best Western Plus Sikeston
$116
starstar
Very Good 4.5   409 Reviews
120 South Interstate Drive Sikeston, MO
  • Pet Friendly
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Pear Tree Inn Cape Girardeau Near the Medical Center
$104
starstar
Very Good 4.0   192 Reviews
3248 William St Cape Girardeau, MO
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Drury Inn & Suites Sikeston MO
$130
starstarstar
Very Good 4.5   445 Reviews
2608 East Malone Ave Sikeston, MO
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Quality Inn Cairo I-57
$72
starstar
Good 3.5   65 Reviews
13201 Kessler Road Cairo, IL
  • Pet Friendly
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Super 8 by Wyndham Sikeston / Miner Area
$65
starstar
Good 3.0   355 Reviews
2609 East Malone Ave Sikeston, MO
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Hampton Inn Cape Girardeau I 55 East
$115
starstar
0 Reviews
207 South Mt. Auburn Rd Cape Girardeau, MO
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