- 42 Available Hotels Near I-581 and Brandon Ave SW
- Rates Starting at just $42.99
- 26 Chains To Choose From
- Last Minute Inventory!
Looking for a place to stay at I-581 and Brandon Ave SW in Roanoke, VA? Hotels-Rates has got you covered with all you need to know about hotels and lodging around this intersection and elsewhere in Roanoke. Whether you are traveling for work or pleasure, we have information on all the things to do, attractions and accomodations in Roanoke. Visiting a university for the first time? Hollins University, Jefferson College of Health Sciences and Roanoke College are quite close to the exit, with Hollins University being the closest.